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Cisco Secure Email vs Cisco Secure Email Threat Defense comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
52
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th), Secure Email Gateway (SEG) (1st)
Cisco Secure Email
Ranking in Email Security
3rd
Average Rating
8.4
Reviews Sentiment
7.0
Number of Reviews
62
Ranking in other categories
Cisco Security Portfolio (7th)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of June 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 12.6%, down from 17.6% compared to the previous year. The mindshare of Cisco Secure Email is 6.4%, down from 8.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Kostas Karidas - PeerSpot reviewer
Helps prevent security breaches but fails to improve in the area of AI
I have not noticed any impressive advanced threat protection mechanisms in the tool. I don't know if there are any AI features in the product. I don't know if there is any other technology embedded in the solution. Cisco Secure Email successfully mitigated potential email threats. My company has seen plenty of scenarios where Cisco Secure Email successfully mitigated potential email threats, spam emails, and fraudulent domains. The product is good for dealing with spam emails, and it can take care of more than 100 spam emails per day. A huge number of spam emails are monitored with the help of Cisco Secure Email. I would not recommend the product to other businesses because you need to have some kind of expertise in configuring and knowing a bit about the tool's GUI. The tool also lacks in the area of AI mechanics. If I would like to have an overview and review another solution, I would go for another product other than Cisco Secure Email. I can definitely suggest others to look at the product and review it, but I would also recommend that they compare it with the other solutions in the market. I wouldn't prioritize Cisco Secure Email over other tools. Either the support partner of the product or I take care of the tool's maintenance phase by looking into the configurations and doing some fine-tuning. I rate the tool a seven to eight out of ten.
Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."
"Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the individuals within our organization who are affected."
"Defender is a SaaS platform, so it offers more flexibility. Managing the permissions is easier. The solution's automated detection and response features are scalable."
"Does a thorough job of examining email and URLs for malicious content."
"The solution is very easy to use. All you have to do is to assign the license to the end-user and it's done. The customer will only have the feature activated, and the solution will monitor the emails to determine if they are a threat or not."
"The deployment capability is a great feature."
"The basic features are okay and I'm satisfied with the Defender."
"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"The most valuable feature is the different content filters we are using, such as DKIM."
"At one point, there was a zero-day attack. The Cisco appliance detected it and stopped it, helping us out. We avoided the attack and potential damage."
"The technical support from Cisco is perfect."
"The added value of it is that every migration to a new version is initiated by the Cisco version itself, so that is a bunch of work that you don't have to do on the Cisco ESA system on-premise. As it becomes a safe platform, you don't need to invest anything in your own data center or in your upgrade path."
"What I find the most valuable about Cisco Secure Email is that the logs are not that difficult to see even if you're not used to them. The logs are reasonably readable and diagnosing the problem is not too hard with them."
"The product blocks spam emails."
"The security features are valuable."
"The filtering is definitely better at catching both spam and malicious messages, and there's a lot of extremely granular ability for setting up rules. You can do it the way you want to. The Microsoft solution tends to be pretty limited in how it allows some of that to be done."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The product offers protection, email security, anti-spam, and antivirus."
"It has an efficient email filtering feature."
"The solution is stable."
"It's very easy to deploy and configure."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
 

Cons

"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"Microsoft Defender for Office 365 could improve by giving customers information on techniques to prevent threats. For example, information about best practices on how to protect their own devices against hackers and scammers, such as educational information or training. This would help others have a better understanding of cyber security. Additionally, there can be more security features added."
"Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published."
"It is not user-friendly, and it is quite complicated. So, it should be more user-friendly."
"I am not satisfied with the solution's reporting and logging."
"The product's GUI for the dashboard needs improvement."
"Better dashboards and more interactive overviews would be nice, but the current functionality is sufficient."
"The graphical user interface is not user-friendly like other vendors. I find it very difficult at times to find some options on the UI."
"The discontinuation of physical hardware solutions is a significant area for improvement in Cisco Email Security Appliance. This decision has posed challenges as virtual appliances are now the only option, which may not be suitable for all industries. The uncertainty regarding the future of the hardware aspect of the solution is a notable concern."
"We have occasionally had hardware problems because we are using an appliance-based solution, but that might change. We may consider going to virtual systems."
"I use the search all the time. Sometimes, it is hard to search for things and things are hard to find. People come to me all the time, saying, "This email didn't get through." Then, I go searching and don't find it on the first search. You have to think about alternative searches. I don't know if there is an easier way that they could help to find things. I don't know how they could simplify it, because now everybody else is using the cloud and everything is coming from Office 365, or whatever. It is just not the same environment from years ago where everybody had their own server and you could search easier."
"This solution could be improved by integration with Sandbox."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The solution is a bit expensive."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The physical appliance has been discontinued, although the platform still exists."
"The pricing could always be better."
 

Pricing and Cost Advice

"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"It's a user-base subscription."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The pricing has become expensive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"We do annual licensing for Cisco Secure Email Gatewayand SMA together, and possibly SmartNet support. Packaged together, the cost is just under $38,000."
"Cisco Secure Email is more expensive than other products. I rate it a five out of ten. There are no additional costs. You only need to pay the subscription amounts."
"In my previous organization, avoiding four instances of CryptoLocker within an estimated six month period is approximately $600,000 in lost time and effort. Our five year cost was about a million dollars, and the four outages that we had equated to 65 percent of that five year cost."
"I don't have the insights into it, but compared to different products, it seems to have a medium level of pricing."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"Pricing depends on your environment and which model you want to buy."
"The price is significantly high."
"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Educational Organization
25%
Computer Software Company
18%
Financial Services Firm
8%
Manufacturing Company
5%
Computer Software Company
30%
Healthcare Company
7%
Government
7%
Financial Services Firm
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Microsoft is quite affordable with a lot of features available for any size organization.
What needs improvement with Microsoft Defender for Office 365?
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS recor...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The user interface of the Email Security Gateway ( /products/security-gateway-reviews ) should be improved. It would ...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
 

Also Known As

MS Defender for Office 365
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Find out what your peers are saying about Cisco Secure Email vs. Cisco Secure Email Threat Defense and other solutions. Updated: June 2025.
855,347 professionals have used our research since 2012.
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